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Contents 1 Defeating the giant worm 2 Defeating Thresher Maw

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Defeating the giant worm

When you are on the mission about the missing Marines you will encounter a large worm creature. To defeat it, jump just before the projectile acid the worm spits. Meanwhile, attack it with missiles (RB) and constant gunfire (RT) and it will soon fall.
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Defeating Thresher Maw

The easiest way to defeat the Thresher Maw is after it has initially launched out of the ground to drive off, stay at a relative distance and drive circles around it while firing. Because of your distance, it will not use its long-ranged attack or be able to cause melee damage. It will go back underground after a time or certain amount of damage is inflicted and will change location where it pops up. Repeat the circular attack and you will get away undamaged.